Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474192 | 0.81 | KDM4E (0.70) | CYP2C9TSHRCYP3A4CYP2D6KDM4E | |
| SCHEMBL7787513 | 0.81 | ITGB3 (0.49) | MMP2ITGB3ITGA2BCYP2C9TSHR | |
| SCHEMBL7787414 | 0.80 | ITGB3 (0.56) | MMP2ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL7788399 | 0.79 | MMP2 (0.49) | MMP2ITGB3ITGA2BCYP2C9TSHR | |
| SCHEMBL3847579 | 0.78 | MAPT (0.55) | CYP2C9TSHRCYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL7782706 | 0.76 | ITGB3 (0.59) | ITGB3ITGA2BKDM4EALDH1A1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL7790815 | 0.76 | ITGB3 (0.47) | ITGB3ITGA2BCYP2C9TSHRCYP3A4 | |
| SCHEMBL7791950 | 0.75 | CYP2D6 (0.43) | MMP2ITGB3ITGA2BCYP2C9TSHR | |
| SCHEMBL7787524 | 0.74 | KDM4E (0.45) | HRH3MMP2CYP2C9TSHRCYP3A4 | |
| SCHEMBL785187 | 0.73 | CHKA (0.53) | ITGB3ITGA2BCYP2C9TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010009912-A1 | NEW DERIVATIVES OF PYRIDIL PIPERAZINE OR PYRIDAZINYL PIPERAZYL, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | TSAKLAKIDIS CHRISTOS (DE) | 2001-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010009912-A1 | NEW DERIVATIVES OF PYRIDIL PIPERAZINE OR PYRIDAZINYL PIPERAZYL, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | CYP4B1, NR4A1, CYP3A43 | HRH3 193/4885MMP2 1302/4885ITGB3 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.