SCHEMBL7792155

SCHEMBL7792155

COc1c(C)cc(CCC(=O)O)cc1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.44
FFAR4 Q5NUL3 5/20 0.44
GAA P10253 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRA P10827 2/20 0.40
THRB P10828 2/20 0.40
FFAR2 O15552 1/20 0.40
KMT2A Q03164 2/20 0.40
VCAM1 P19320 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796603 0.91 GAA (0.45) FFAR1GAARXRARXRBRXRG
SCHEMBL3669296 0.87 NPSR1 (0.52) FFAR1FFAR4NPSR1THRATHRB
SCHEMBL7792867 0.87 FFAR4 (0.41) FFAR1FFAR4RXRANPSR1THRA
SCHEMBL35210191 0.87 GAA (0.47) GAAKMT2AVCAM1
SCHEMBL7796633 0.86 FFAR4 (0.41) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL7942452 0.86 FFAR4 (0.45) FFAR1FFAR4GAARXRARXRB
SCHEMBL7796619 0.85 NR1H4 (0.45) GAARXRARXRBRXRGTHRA
SCHEMBL35210206 0.85 ALDH1A1 (0.46) GAAKMT2A
SCHEMBL7792806 0.84 GAA (0.41) FFAR1FFAR4GAARXRARXRB
SCHEMBL7792487 0.83 GAA (0.40) FFAR1GAARXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed