Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | THRA | P10827 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952084 | 0.90 | THRA (0.58) | FFAR4THRATHRB | |
| SCHEMBL7792155 | 0.87 | FFAR1 (0.44) | NPSR1FFAR4FFAR1THRATHRB | |
| SCHEMBL10750673 | 0.87 | NPC1 (0.50) | FFAR4FFAR1THRATHRBALDH1A1 | |
| SCHEMBL14553370 | 0.84 | FFAR1 (0.55) | FFAR4FFAR1THRATHRBALDH1A1 | |
| SCHEMBL7792867 | 0.84 | FFAR4 (0.41) | NPSR1FFAR4FFAR1THRATHRB | |
| SCHEMBL429622 | 0.83 | KMT2A (0.57) | — | |
| SCHEMBL7796633 | 0.83 | FFAR4 (0.41) | NPSR1FFAR4FFAR1THRATHRB | |
| SCHEMBL7523213 | 0.82 | NPSR1 (0.55) | NPSR1FFAR4FFAR1THRATHRB | |
| SCHEMBL12560457 | 0.82 | FFAR4 (0.48) | NPSR1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL18258239 | 0.82 | NPSR1 (0.57) | NPSR1FFAR4FFAR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2016-03-17 | — | — | US | disclosed |
| WO-2014121327-A1 | RADICAL ORBITAL SWITCHING | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2014-08-14 | — | — | WO | disclosed |
| US-7812038-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2010-10-12 | — | — | US | disclosed |
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | BIEDIGER RONALD J | 2006-12-07 | — | — | US | disclosed |
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276476-A1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | VCAM1, ICAM1, ITGA1 | NPSR1 1388/4885FFAR4 107/4885FFAR1 74/4885 |
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | RAD1, RAD54L, NQO1 | NPSR1 1873/4885FFAR4 4384/4885FFAR1 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.