Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830812 | 0.84 | TACR1 (0.45) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL2039023 | 0.83 | TACR1 (0.44) | TACR1TACR3CYP2C19MAPTALDH1A1 | |
| SCHEMBL9168218 | 0.83 | TACR1 (0.44) | TACR1TACR3CYP3A4TSHRTP53 | |
| SCHEMBL22211342 | 0.83 | TACR1 (0.44) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL4809720 | 0.83 | TACR1 (0.55) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL8830633 | 0.81 | TACR1 (0.51) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL8830792 | 0.81 | TACR1 (0.43) | TACR1TACR3MAPTGPR119ALDH1A1 | |
| SCHEMBL22211320 | 0.80 | TACR1 (0.42) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL8830648 | 0.80 | GPR119 (0.45) | TACR1TACR3CYP3A4TSHRCYP2C19 | |
| SCHEMBL16166076 | 0.80 | TACR1 (0.45) | TACR1TACR3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001081066-A | SUBSTITUTED STYRENE DERIVATIVE | NIPPON PETROCHEM CO LTD | 2001-03-27 | — | — | JP | disclosed |