SCHEMBL7792402

SCHEMBL7792402

CCCCc1cc(F)c(/C=N/N=C/c2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
TRPA1 O75762 1/20 0.36
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTGS2 P35354 3/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792405 1.00 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7789287 0.96 PTGS2 (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7789286 0.96 PTGS2 (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7788415 0.94 PTGS2 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7788412 0.94 PTGS2 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7791223 0.91 TRPA1 (0.38) TRPA1
SCHEMBL7791221 0.91 TRPA1 (0.38) TRPA1
SCHEMBL7792457 0.86 GRIN1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7792454 0.86 GRIN1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7788581 0.84 TRPA1 (0.40) TRPA1NPC1MAPK1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed