SCHEMBL7788581

SCHEMBL7788581

CCc1cc(F)c(C=NN=Cc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31
THPO P40225 1/20 0.31
NPC1 O15118 1/20 0.31
CHRM5 P08912 1/20 0.31
GRM5 P41594 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788578 1.00 TRPA1 (0.40) TRPA1CYP1A2CYP3A4CYP2D6PKM
SCHEMBL7791223 0.87 TRPA1 (0.38) TRPA1PKM
SCHEMBL7791221 0.87 TRPA1 (0.38) TRPA1PKM
SCHEMBL7792405 0.84 GRIN2D (0.38) TRPA1CYP3A4MAPK1NPC1RAB9A
SCHEMBL7792402 0.84 GRIN2D (0.38) TRPA1CYP3A4MAPK1NPC1RAB9A
SCHEMBL7793448 0.84 TRPA1 (0.42) TRPA1CYP1A2CYP3A4CYP2D6PKM
SCHEMBL7793450 0.84 TRPA1 (0.42) TRPA1CYP1A2CYP3A4CYP2D6PKM
SCHEMBL7788227 0.83 MAOA (0.40) CYP1A2CYP3A4CYP2D6PKMMAPK1
SCHEMBL7788223 0.83 MAOA (0.40) CYP1A2CYP3A4CYP2D6PKMMAPK1
SCHEMBL7789286 0.83 PTGS2 (0.37) TRPA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed