Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16381560 | 0.86 | DRD2 (0.46) | KDM4ESMN1; SMN2ALDH1A1DRD2 | |
| SCHEMBL7796227 | 0.79 | CHRNA1 (0.40) | NPC1ALDH1A1 | |
| SCHEMBL7795756 | 0.77 | CHRNA1 (0.46) | KDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL7786361 | 0.73 | CYP19A1 (0.49) | LMNAKDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL19002080 | 0.72 | MEN1 (0.38) | KDM4ETSHRNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9277221 | 0.71 | SLC6A2 (0.39) | ALDH1A1 | |
| SCHEMBL6302031 | 0.71 | CHRNA1 (0.50) | LMNAKDM4ENPC1GAADRD2 | |
| SCHEMBL10637412 | 0.71 | CHRNA1 (0.33) | ALDH1A1 | |
| SCHEMBL18555663 | 0.69 | KDM4E (0.41) | LMNAKDM4ETSHRGAASMN1; SMN2 | |
| SCHEMBL29639264 | 0.69 | HTR2C (0.53) | LMNAKDM4ETSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160309-C | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | �ճ�˹�������³˹��˾ | 2004-08-04 | — | — | CN | disclosed |
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| CN-1220660-A | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-23 | — | — | CN | disclosed |
| EP-0906268-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045397-A1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-04 | — | — | WO | disclosed |