Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP12 | P39900 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP16 | P51512 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725131 | 0.86 | PTGS2 (0.49) | NR1H4MMP2MMP12MMP8MMP13 | |
| SCHEMBL30100028 | 0.86 | PTGS2 (0.49) | NR1H4MMP2MMP12MMP8MMP13 | |
| SCHEMBL7796121 | 0.84 | NR1H4 (0.44) | NR1H4AKR1B1TDP1FABP4FABP5 | |
| SCHEMBL7796396 | 0.84 | NR1H4 (0.47) | NR1H4TNFRSF1A | |
| SCHEMBL9079419 | 0.84 | AKR1B1 (0.52) | MMP2MMP12MMP8MMP13MMP14 | |
| SCHEMBL3235703 | 0.83 | NR1H4 (0.43) | NR1H4MMP2MMP12MMP8MMP13 | |
| SCHEMBL25450879 | 0.81 | GABRA1 (0.43) | NR1H4TDP1TNFRSF1A | |
| SCHEMBL12477045 | 0.80 | PTGDR2 (0.47) | NR1H4MMP2MMP12MMP8MMP13 | |
| SCHEMBL16154153 | 0.80 | CA2 (0.42) | NR1H4TDP1TNFRSF1A | |
| SCHEMBL3852706 | 0.79 | AKR1B1 (0.55) | NR1H4MMP2MMP12MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823435-B1 | Phosphites, process for producing the same and their use | SUMITOMO CHEMICAL CO (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5889095-A | OXYGEN AND HEAT RESISTANCE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0823435-A2 | Phosphites, process for producing the same and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-02-11 | — | — | EP | disclosed |