SCHEMBL7792480

SCHEMBL7792480

Cc1ccc(-c2ccc(C=NN=Cc3ccc(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.50
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HDAC1 Q13547 3/20 0.40
KDM1A O60341 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC2 Q92769 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791196 0.91 NPC1 (0.57) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7792208 0.91 NPC1 (0.57) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7791151 0.88 NPC1 (0.48) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7792488 0.84 NPC1 (0.65) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7792491 0.84 NPC1 (0.65) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7791384 0.83 NPC1 (0.43) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7789206 0.82 NPC1 (0.46) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7792424 0.82 NPC1 (0.46) NFE2L2NPC1RAB9ASMN1; SMN2CASP3
SCHEMBL7793412 0.82 PLA2G7 (0.35) NFE2L2NPC1RAB9ASMN1; SMN2GRIN1
SCHEMBL7783517 0.81 NFE2L2 (0.56) NFE2L2NPC1RAB9ASMN1; SMN2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed