SCHEMBL7792633

SCHEMBL7792633

CCc1cc(CC(=O)O)cc(C(C)(C)CC(C)(C)C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.43
THRB P10828 7/20 0.35
THRA P10827 6/20 0.35
RXRA P19793 2/20 0.35
PPARG P37231 2/20 0.35
ITGB3 P05106 1/20 0.35
ITGAV P06756 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
GAA P10253 4/20 0.33
TSHR P16473 2/20 0.33
NFKB1 P19838 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RGS12 O14924 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792869 0.88 HSPA5 (0.45) HSPA5THRBTHRARXRAPPARG
SCHEMBL7942304 0.86 HSPA5 (0.41) HSPA5THRBTHRARXRAALDH1A1
SCHEMBL7792902 0.85 ALDH1A1 (0.44) ALDH1A1HPGDGAATSHRNFKB1
SCHEMBL7792635 0.85 ALDH1A1 (0.41) HSPA5THRBTHRAALDH1A1HPGD
SCHEMBL7796135 0.84 HSPA5 (0.60) HSPA5THRBTHRARXRAPPARG
SCHEMBL7792782 0.84 HMGB1 (0.38) THRBTHRARXRAPPARGITGB3
SCHEMBL7795934 0.82 THRB (0.39) THRBTHRARXRAPPARGITGB3
SCHEMBL27315571 0.81 HSPA5 (0.44) HSPA5ALDH1A1HPGDGAATSHR
SCHEMBL3805391 0.81 HSPA5 (0.44) HSPA5THRBALDH1A1HPGDHSD17B10
SCHEMBL2917130 0.79 HSPA5 (0.43) HSPA5ALDH1A1HPGDGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed