SCHEMBL7795934

SCHEMBL7795934

CCc1cc(CC(=O)O)cc(C(C)(C)CC(C)(C)C)c1OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.39
THRA P10827 6/20 0.39
NR1H4 Q96RI1 2/20 0.36
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.35
PTGS1 P23219 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA5A P35218 1/20 0.35
RXRA P19793 2/20 0.33
ITGB3 P05106 1/20 0.33
ITGAV P06756 1/20 0.33
PPARG P37231 1/20 0.33
ACLY P53396 1/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792544 0.89 THRB (0.40) THRBTHRANR1H4GAAALDH1A1
SCHEMBL7794852 0.87 THRA (0.40) THRBTHRARXRARXRBRXRG
SCHEMBL7786485 0.86 NR1H4 (0.43) THRBTHRANR1H4GAAALDH1A1
SCHEMBL7786480 0.86 NR1H4 (0.44) THRBTHRANR1H4GAAALDH1A1
SCHEMBL7795937 0.86 THRB (0.44) THRBTHRANR1H4GAAALDH1A1
SCHEMBL7795884 0.85 THRB (0.37) THRBTHRANR1H4GAAALDH1A1
SCHEMBL6565884 0.82 MAPT (0.35)
SCHEMBL7792633 0.82 HSPA5 (0.43) THRBTHRAGAAALDH1A1TSHR
SCHEMBL6565863 0.81 TNKS2 (0.39)
SCHEMBL7796420 0.81 TPMT (0.39) ALDH1A1TSHRTDP1CA5ARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed