Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935128 | 0.79 | CA12 (0.58) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL7080547 | 0.79 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL11518894 | 0.79 | L3MBTL1 (0.79) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL3200467 | 0.78 | MEN1 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL20981664 | 0.77 | L3MBTL1 (0.82) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL10073227 | 0.75 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL26623605 | 0.75 | L3MBTL1 (0.49) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL18247723 | 0.75 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 | |
| SCHEMBL5572981 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2ALMNAGPR35 | |
| SCHEMBL24350476 | 0.75 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP2C9CYP2C19CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723962-B1 | Arylalkyl-thiadiazinones | MERCK PATENT GMBH (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-0723962-A1 | Arylalkyl-thiadiazinones | MERCK PATENT GmbH (DE) | 1996-07-31 | — | — | EP | disclosed |