SCHEMBL7792776

SCHEMBL7792776

CCOc1c(C)cc(C(C)(C)C)cc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.45
PPARG P37231 2/20 0.45
RARG P13631 1/20 0.45
RXRB P28702 1/20 0.45
CD69 Q07108 2/20 0.42
ELANE P08246 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NR1H4 Q96RI1 2/20 0.42
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
GRIN2C Q14957 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792127 0.86 RXRA (0.59) RXRAPPARGRARGRXRBCD69
SCHEMBL9190271 0.84 RXRA (0.58) RXRAPPARGRARGRXRBCD69
SCHEMBL7786427 0.81 RXRB (0.49) RXRAPPARGRARGRXRBCD69
SCHEMBL12401801 0.80 POLB (0.43) RXRAPPARGRARGCD69ELANE
SCHEMBL9187455 0.80 RXRB (0.47) RXRAPPARGRARGRXRBCD69
SCHEMBL7933809 0.80 GAA (0.38) RXRAPPARGRARGCD69ELANE
SCHEMBL7794927 0.78 RXRA (0.50) RXRAPPARGRARGRXRBCD69
SCHEMBL7792928 0.76 RXRA (0.44) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL7786411 0.76 NR1H4 (0.50) RXRAPPARGRARGRXRBCD69
SCHEMBL1546979 0.74 TDP1 (0.49) RXRARXRBTDP1NR1H4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed