SCHEMBL7794927

SCHEMBL7794927

CCOc1c(C)cc(C(C)(C)C)cc1CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.50
RXRB P28702 2/20 0.50
THRB P10828 1/20 0.45
NR1H4 Q96RI1 5/20 0.45
CD69 Q07108 2/20 0.43
ELANE P08246 1/20 0.43
RXRG P48443 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RARG P13631 1/20 0.39
PPARG P37231 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
CYP2C19 P33261 1/20 0.38
EPHX2 P34913 1/20 0.38
ALDH1A1 P00352 1/20 0.38
AGBL2 Q5U5Z8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786586 0.87 RXRA (0.51) RXRARXRBTHRBNR1H4CD69
SCHEMBL7786411 0.85 NR1H4 (0.50) RXRARXRBNR1H4CD69ELANE
SCHEMBL7796088 0.84 RXRA (0.52) RXRARXRBNR1H4CD69ELANE
SCHEMBL8433459 0.81 MAPT (0.38) RXRARXRBCD69ELANESMN1; SMN2
SCHEMBL10046749 0.80 CD69 (0.59) RXRARXRBNR1H4CD69ELANE
SCHEMBL7792776 0.78 RXRA (0.45) RXRARXRBTHRBNR1H4CD69
SCHEMBL12401801 0.78 POLB (0.43) RXRANR1H4CD69ELANESMN1; SMN2
SCHEMBL7795955 0.78 THRB (0.44) RXRARXRBTHRBSMN1; SMN2RARG
SCHEMBL18050429 0.76 RXRA (0.42) RXRARXRBNR1H4CD69ELANE
SCHEMBL18050555 0.76 RXRA (0.48) RXRARXRBNR1H4CD69ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed