SCHEMBL7792928

SCHEMBL7792928

CCOc1c(C(=O)O)cc(C)cc1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.44
PPARG P37231 2/20 0.44
RARG P13631 1/20 0.44
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
IDO1 P14902 1/20 0.39
CA2 P00918 1/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
NOTUM Q6P988 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5908087 0.87 RXRA (0.47) RXRAPPARGRARGALDH1A1SMN1; SMN2
SCHEMBL7792127 0.84 RXRA (0.59) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL9190271 0.83 RXRA (0.58) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL7796467 0.82 HSD17B10 (0.45) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL7942361 0.80 RXRA (0.38) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL7795955 0.79 THRB (0.44) RXRAPPARGRARGHSD17B10ALDH1A1
SCHEMBL7792646 0.77 TSHR (0.42) RXRAPPARGRARGTSHRPOLB
SCHEMBL7792696 0.77 NPSR1 (0.42) RXRAPPARGRARGSMN1; SMN2
SCHEMBL7792776 0.76 RXRA (0.45) RXRAPPARGRARGTSHRHSD17B10
SCHEMBL7796086 0.76 LMNA (0.44) RXRAPPARGRARGHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed