Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.60 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792804 | 1.00 | CTSL (0.66) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL3251530 | 0.96 | CTSL (0.65) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL3251534 | 0.96 | CTSL (0.65) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| Hydrochloric Acid SCHEMBL3176226 | 0.95 | CTSL (0.64) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| Hydrochloric Acid SCHEMBL3176223 | 0.95 | CTSL (0.64) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL2367228 | 0.90 | ITGB3 (0.64) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL1841202 | 0.90 | PRSS1 (0.61) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL1841203 | 0.90 | PRSS1 (0.61) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL210601 | 0.90 | ITGB3 (0.64) | CTSLPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL210602 | 0.90 | ITGB3 (0.64) | CTSLPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902780-B1 | QUATERNARY CYTOFECTINS | VICAL INC (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0902780-A1 | QUATERNARY CYTOFECTINS | VICAL INCORPORATED (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997037966-A1 | QUATERNARY CYTOFECTINS | VICAL INCORPORATED (US) | 1997-10-16 | — | — | WO | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |