Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.61 |
| ▸ | ECE1 | P42892 | 1/20 | 0.61 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210602 | 1.00 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL2367228 | 1.00 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL2500832 | 0.99 | ITGB3 (0.63) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL287474 | 0.96 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6476819 | 0.96 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL287475 | 0.96 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL15968143 | 0.96 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL24188458 | 0.95 | ECE1 (0.62) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL4994643 | 0.95 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL21219335 | 0.95 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748609-B2 | Catalysis of diketopiperazine synthesis | MANNKIND CORPORATION (US) | 2014-06-10 | — | — | US | claimed |
| US-20120178935-A1 | Catalysis of Diketopiperazine Synthesis | MANNKIND CORPORATION (US) | 2012-07-12 | — | — | US | claimed |
| US-8202992-B2 | Catalysis of diketopiperazine synthesis | MANNKIND CORPORATION (US) | 2012-06-19 | — | — | US | claimed |
| US-20100087642-A1 | Catalysis of Diketopiperazine Synthesis | MANNKIND CORPORATION (US) | 2010-04-08 | — | — | US | claimed |
| EP-1088020-B1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE (CZ) | 2002-12-18 | — | — | EP | claimed |
| EP-1088020-A1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2001-04-04 | — | — | EP | claimed |
| WO-1999064495-A1 | FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) | 1999-12-16 | — | — | WO | claimed |
| US-3936469-A | Process for preparing N-carboxylic anhydrides of amino acids | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | claimed |
| US-20260042739-A1 | Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine | MANNKIND CORP (US) | 2026-02-12 | — | — | US | disclosed |
| US-12465582-B2 | (S)-2-amino-6-((3-aminopropyl)amino)hexanoic acid (APL) for use in the treatment of non-alcoholic steatohepatitis (NASH), liver inflammation, hepatocellular ballooning, liver fibrosis and steatosis | Temple University—Of the Commonwealth System of Higher Education (US) | 2025-11-11 | — | — | US | disclosed |
| US-12459903-B2 | Formation of n-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine | MANNKIND CORPORATION (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4595969-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | Temple University Of The Commonwealth System Of Higher Education (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250241943-A1 | BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS | CALM WATER THERAPEUTICS LLC | 2025-07-31 | — | — | US | disclosed |
| WO-2025151642-A1 | MODIFIED ELONGATION FACTOR P AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2025-07-17 | — | — | WO | disclosed |
| EP-0230037-A1 | Cytoprotective derivatives useful in ischemic diseases, their preparation and compositions containing them | ITALFARMACO S.p.A. (IT) | 1987-07-29 | — | — | EP | disclosed |
| US-4616012-A | BENZOTHIADIZINYL AND QUINAZOLINYL DERIVATIVES | SCHERING CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0157572-A2 | Acyltripeptide immunostimulants | PFIZER INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0017309-A1 | Cyclic hexapeptide and dipeptide and compositions containing them | MERCK & CO. INC. (US) | 1980-10-15 | — | — | EP | disclosed |
| US-3936469-A | Process for preparing N-carboxylic anhydrides of amino acids | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042739-A1 | Formation of N-Protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine | ACMSD, DNPEP, PGM2 | ITGB3 4201/4885ITGA2B 4448/4885PRSS1 1750/4885 |
| US-20100087642-A1 | Catalysis of Diketopiperazine Synthesis | PHYKPL, DNPEP, NPEPPS | ITGB3 4092/4885ITGA2B 4360/4885PRSS1 807/4885 |
| US-12459903-B2 | Formation of n-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine | PGM2, DNPEP, NPEPPS | ITGB3 4215/4885ITGA2B 4688/4885PRSS1 1809/4885 |
| US-20120178935-A1 | Catalysis of Diketopiperazine Synthesis | PHYKPL, DNPEP, NPEPPS | ITGB3 4092/4885ITGA2B 4360/4885PRSS1 807/4885 |
| US-12465582-B2 | (S)-2-amino-6-((3-aminopropyl)amino)hexanoic acid (APL) for use in the treatment of non-alcoholic steatohepatitis (NASH), liver inflammation, hepatocellular ballooning, liver fibrosis and steatosis | FABP1, AADAT, FABP6 | ITGB3 2210/4885ITGA2B 1846/4885PRSS1 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.