SCHEMBL7792860

SCHEMBL7792860

COc1ccc(CCC(=O)O)cc1C1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 13/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
EPHX1 P07099 1/20 0.49
SELP P16109 1/20 0.48
PTGDR Q13258 6/20 0.48
PTGER2 P43116 1/20 0.48
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792682 0.86 PTGDR2 (0.57) PTGDR2SELPPTGDRPTGER2
SCHEMBL8574560 0.85 GAA (0.57) PTGDR2SELPPTGDRPTGER2
SCHEMBL31254180 0.84 THRA (0.52) PTGDR2PTGDRPTGER2FFAR1FFAR4
SCHEMBL7941422 0.84 MEN1 (0.50) PTGDR2MEN1KMT2AEPHX1PTGDR
SCHEMBL31254179 0.84 PTGDR2 (0.58) PTGDR2PTGDRPTGER2FFAR1FFAR4
SCHEMBL6565778 0.83 NUDT1 (0.48) PTGDR2MEN1KMT2AEPHX1PTGDR
SCHEMBL7420826 0.83 PDE4A (0.57) MEN1KMT2AEPHX1
SCHEMBL8984904 0.82 MEN1 (0.46) PTGDR2MEN1KMT2AEPHX1FFAR1
SCHEMBL7335293 0.82 PDE4A (0.58) MEN1KMT2A
SCHEMBL6567763 0.81 TNKS2 (0.47) PTGDR2MEN1KMT2AEPHX1PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed