SCHEMBL7792890

SCHEMBL7792890

CC(C)(C)c1cc(CC(=O)O)cc(C2CCCCC2)c1O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.45
PTGDR2 Q9Y5Y4 8/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
THRA P10827 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
GAA P10253 2/20 0.38
PTGDR Q13258 3/20 0.38
PTGER2 P43116 1/20 0.38
GLRA3 O75311 1/20 0.37
GLRB P48167 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
GPR55 Q9Y2T6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796368 0.87 KMT2A (0.47) THRBPTGDR2KDM4EALDH1A1TDP1
SCHEMBL8772283 0.84 ALDH1A1 (0.45) THRBKDM4EALDH1A1TDP1MEN1
SCHEMBL7786559 0.84 THRB (0.46) THRBPTGDR2ALDH1A1TDP1THRA
SCHEMBL9182008 0.82 ALDH1A1 (0.43) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL7792886 0.82 THRB (0.47) THRBPTGDR2KDM4ETHRAMEN1
SCHEMBL9182462 0.81 ALDH1A1 (0.42) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL6567025 0.81 ALDH1A1 (0.42) THRBKDM4EALDH1A1TDP1MEN1
SCHEMBL9176613 0.81 ALDH1A1 (0.42) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL9181332 0.81 ALDH1A1 (0.42) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL9184712 0.81 ALDH1A1 (0.42) KDM4EALDH1A1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed