Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.46 |
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792116 | 0.86 | THRA (0.45) | THRBPTGDR2THRAS1PR1S1PR5 | |
| SCHEMBL7795915 | 0.84 | THRB (0.46) | THRBPTGDR2THRAS1PR1S1PR5 | |
| SCHEMBL8772352 | 0.83 | SHBG (0.44) | THRBPTGDR2THRAKDM4EMEN1 | |
| SCHEMBL7792890 | 0.82 | THRB (0.45) | THRBPTGDR2THRAKDM4EMEN1 | |
| SCHEMBL7792920 | 0.82 | THRB (0.49) | THRBPTGDR2THRAS1PR1S1PR5 | |
| SCHEMBL27861753 | 0.80 | NUDT1 (0.48) | THRBPTGDR2THRAKDM4EMEN1 | |
| SCHEMBL9182898 | 0.80 | NUDT1 (0.44) | PTGDR2S1PR1S1PR5KDM4EMEN1 | |
| SCHEMBL11801393 | 0.79 | NUDT1 (0.40) | THRBPTGDR2THRAKDM4EMEN1 | |
| SCHEMBL9182186 | 0.79 | NUDT1 (0.43) | PTGDR2S1PR1S1PR5KDM4EMEN1 | |
| SCHEMBL9178157 | 0.79 | NUDT1 (0.43) | PTGDR2S1PR1S1PR5KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823435-B1 | Phosphites, process for producing the same and their use | SUMITOMO CHEMICAL CO (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5889095-A | OXYGEN AND HEAT RESISTANCE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0823435-A2 | Phosphites, process for producing the same and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-02-11 | — | — | EP | disclosed |