SCHEMBL7792896

SCHEMBL7792896

CCC(C)(C)c1cc(CC(=O)O)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.56
HSD17B10 Q99714 6/20 0.56
KDM4E B2RXH2 5/20 0.56
GAA P10253 4/20 0.56
MAPT P10636 4/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
NFKB1 P19838 2/20 0.56
POLB P06746 2/20 0.56
APEX1 P27695 2/20 0.56
BLM P54132 2/20 0.56
PMP22 Q01453 2/20 0.56
RGS12 O14924 1/20 0.56
LMNA P02545 1/20 0.56
THPO P40225 1/20 0.56
GNAI1 P63096 1/20 0.56
HIF1A Q16665 1/20 0.56
CA2 P00918 3/20 0.56
ALDH1A1 P00352 7/20 0.51
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796462 0.86 HPGD (0.54) HPGDHSD17B10KDM4EGAAMAPT
SCHEMBL7792132 0.85 HSD17B10 (0.61) HPGDHSD17B10KDM4EGAAMAPT
SCHEMBL2491545 0.84 IAPP (0.46) LMNACA2ALDH1A1CA1RXRA
SCHEMBL7796464 0.84 ALDH1A1 (0.49) HPGDHSD17B10KDM4EGAAMAPT
SCHEMBL9489396 0.81 ESR1 (0.48) HSD17B10KDM4EGAAMAPTTSHR
SCHEMBL7796102 0.80 GAA (0.59) HSD17B10GAATSHRTDP1NFKB1
SCHEMBL7786499 0.77 ALDH1A1 (0.45) HPGDKDM4EGAAMAPTTSHR
SCHEMBL3808961 0.77 BACE1 (0.53) HSD17B10KDM4EGAAMAPTTSHR
SCHEMBL3805383 0.77 RARB (0.51) KDM4EGAAMAPTPOLBAPEX1
SCHEMBL7940252 0.76 HMGB1 (0.39) HPGDHSD17B10KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed
CN-88100675-A ANTIOXIDANT AROMATIC FLUOROPHOSPHITES 1988-11-09 CN disclosed