SCHEMBL2491545

SCHEMBL2491545

CCC(C)(C)c1cc(CCC(=O)O)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IAPP P10997 3/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
FFAR1 O14842 5/20 0.42
THRA P10827 2/20 0.41
THRB P10828 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KEAP1 Q14145 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ALDH1A1 P00352 1/20 0.39
ALOX5 P09917 1/20 0.39
OR51E2 Q9H255 1/20 0.39
KAT8 Q9H7Z6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786552 0.87 RXRA (0.44) IAPPRXRARXRBRXRGFFAR1
SCHEMBL1537791 0.86 RXRA (0.53) IAPPRXRARXRBRXRGFFAR1
SCHEMBL7786554 0.85 IAPP (0.48) IAPPRXRAFFAR1FFAR4ALOX5
SCHEMBL7792896 0.84 HPGD (0.56) RXRARXRBRXRGTHRATHRB
SCHEMBL27381689 0.84 ALOX5 (0.46) IAPPALDH1A1ALOX5OR51E2
Ethylene SCHEMBL30206965 0.83 RXRA (0.50) IAPPRXRARXRBRXRGFFAR1
SCHEMBL10556414 0.83 GAA (0.49) RXRARXRBRXRGFFAR1THRA
SCHEMBL7794917 0.81 FFAR1 (0.48) RXRARXRBRXRGFFAR1FFAR4
SCHEMBL3808961 0.81 BACE1 (0.53) IAPPLMNACA2ALDH1A1ALOX5
SCHEMBL27653761 0.80 APP (0.53) IAPPALOX5OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101205317-B Preparation of high-damping rubber containing hindered phenol terminated hyper branched polymer UNIV BEIJING CHEMICAL 2011-06-15 CN claimed
CN-101205317-A Preparation of high-damping rubber containing hindered phenol terminated hyper branched polymer UNIV BEIJING CHEMICAL (CN) 2008-06-25 CN claimed
WO-2020021920-A1 ADHESIVE AGENT AND ADHESIVE SHEET 東洋インキSCホールディングス株式会社 2020-01-30 WO disclosed
JP-2011201806-A NEW COMPOUND HAVING PLANT GROWTH-REGULATING ACTION AND METHOD FOR PRODUCING THE SAME SHIZUOKA SHOKO KAIGISHO 2011-10-13 JP disclosed
CN-101205317-B Preparation of high-damping rubber containing hindered phenol terminated hyper branched polymer UNIV BEIJING CHEMICAL 2011-06-15 CN disclosed
CN-101205317-A Preparation of high-damping rubber containing hindered phenol terminated hyper branched polymer UNIV BEIJING CHEMICAL (CN) 2008-06-25 CN disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed