Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792782 | 0.86 | HMGB1 (0.38) | HMGB1CXCL12NR1H4THRBTHRA | |
| SCHEMBL7786499 | 0.86 | ALDH1A1 (0.45) | CYP1A2CYP2C19CYP2C9GAAHPGD | |
| SCHEMBL283522 | 0.85 | CYP1A2 (0.52) | HMGB1CXCL12NR1H4THRBTHRA | |
| SCHEMBL5850665 | 0.85 | GAA (0.42) | HMGB1CXCL12THRBTHRARXRA | |
| SCHEMBL7792869 | 0.84 | HSPA5 (0.45) | THRBTHRARXRAPPARGITGB3 | |
| SCHEMBL7792784 | 0.84 | ALDH1A1 (0.41) | HMGB1CXCL12NR1H4THRBTHRA | |
| SCHEMBL4915927 | 0.82 | SHBG (0.47) | HMGB1CXCL12ESR1ESR2CYP1A2 | |
| SCHEMBL7796602 | 0.81 | THRB (0.40) | NR1H4THRBTHRARXRAPPARG | |
| SCHEMBL5850773 | 0.80 | MAPT (0.42) | GAATDP1POLBMAPT | |
| SCHEMBL10602464 | 0.80 | SHBG (0.42) | HMGB1CXCL12ESR1ESR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |