Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7798729 | 0.99 | SLC18A3 (0.49) | SLC18A3HPGDALDH1A1KDM4ECYP2C9 | |
| SCHEMBL9299353 | 0.73 | HPGD (0.60) | HPGDALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL28637086 | 0.73 | CES2 (0.54) | HPGDALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL12015481 | 0.71 | SLC18A3 (0.40) | SLC18A3HPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27498542 | 0.71 | OPRM1 (0.49) | SLC18A3ALDH1A1KDM4ECYP2C9GAA | |
| SCHEMBL5523739 | 0.71 | OPRM1 (0.49) | SLC18A3ALDH1A1KDM4ECYP2C9GAA | |
| SCHEMBL27052234 | 0.71 | CES2 (0.48) | HPGDALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL27052395 | 0.71 | CES2 (0.48) | HPGDALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL7581128 | 0.71 | POLB (0.74) | HPGDALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL30158277 | 0.70 | HPGD (0.45) | HPGDALDH1A1KDM4ECYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720605-B1 | AMINOCYCLOHEXYLESTERS AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2001-12-19 | — | — | EP | claimed |