Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470878 | 0.83 | MEN1 (0.53) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9380274 | 0.80 | KMT2A (0.87) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1471429 | 0.79 | KMT2A (0.56) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1470632 | 0.79 | MEN1 (0.52) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1472992 | 0.78 | KMT2A (0.55) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10780921 | 0.77 | ALDH1A1 (0.77) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9505550 | 0.76 | KMT2A (0.52) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL3593065 | 0.76 | KMT2A (0.49) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4176467 | 0.76 | FADS1 (0.54) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL1471326 | 0.75 | KMT2A (0.47) | KMT2AMEN1LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150963-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Aventis Pharma Deutschland GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046214-A1 | SUBSTITUTED 4-AMINO-2-ARYLTETRAHYDROQUINAZOLINES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-08-10 | — | — | WO | disclosed |