Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793269 | 1.00 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL7788273 | 0.84 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL7788268 | 0.84 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL28964176 | 0.83 | PTGS2 (0.60) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL2608307 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL11743247 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL8153257 | 0.82 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL8144434 | 0.81 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL8144432 | 0.81 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL13906334 | 0.81 | NFE2L2 (0.67) | CYP1A1CYP1B1NFE2L2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |