SCHEMBL779332

SCHEMBL779332

O=S(=O)(O)c1ccccc1C(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TTR P02766 2/20 0.38
PGAM1 P18669 1/20 0.37
FABP4 P15090 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
MAPK14 Q16539 1/20 0.35
NR4A1 P22736 1/20 0.34
HSD11B1 P28845 1/20 0.34
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
KCNH2 Q12809 2/20 0.33
CYP1A2 P05177 2/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP12 P39900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777112 0.83 MYC (0.46) MYCTSHRSMN1; SMN2TTRPGAM1
SCHEMBL29102652 0.83 MYC (0.38) MYCTSHRSMN1; SMN2TTRPGAM1
SCHEMBL719364 0.82 GAA (0.44) HSD11B1HTR2AHTR2CKCNH2MMP1
SCHEMBL28725538 0.82 TTR (0.39) MYCTSHRSMN1; SMN2TTRPGAM1
SCHEMBL8078709 0.80 MYC (0.41) MYCTSHRSMN1; SMN2TTRPGAM1
SCHEMBL3181729 0.79 MYC (0.35) MYCTSHRSMN1; SMN2TTRPGAM1
SCHEMBL29933194 0.78 CA2 (0.50) CDK2
SCHEMBL28930136 0.78 TRPV4 (0.44) HSD11B1HTR2AHTR2CKCNH2MMP1
SCHEMBL21826752 0.78 CA2 (0.50) CDK2
SCHEMBL10569917 0.78 MYC (0.40) MYCTSHRSMN1; SMN2TTRPGAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454273-A Polycyclic carbonyl pyridinone compounds and pharmaceutical use thereof 吉利德科学公司 2020-07-28 CN disclosed
CN-107108643-B Polycyclic carbonyl pyridinone compounds and pharmaceutical use thereof 吉利德科学公司 2020-06-05 CN disclosed
US-9608291-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-28 US disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20150188192-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed