SCHEMBL719364

SCHEMBL719364

O=S(=O)(c1ccccc1C(F)F)c1ccccc1C(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
HSD11B1 P28845 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MMP2 P08253 3/20 0.39
MMP9 P14780 3/20 0.39
MMP8 P22894 3/20 0.39
MMP12 P39900 3/20 0.39
MMP13 P45452 3/20 0.39
MMP14 P50281 3/20 0.39
MMP16 P51512 3/20 0.39
MMP1 P03956 2/20 0.39
HTR2A P28223 2/20 0.38
HTR2C P28335 2/20 0.38
KCNH2 Q12809 2/20 0.38
HTR6 P50406 3/20 0.35
MMP3 P08254 2/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29933194 0.82 CA2 (0.50) CA1CA2CA4CA6CA12
SCHEMBL779332 0.82 MYC (0.40) GAAHSD11B1MMP2MMP9MMP8
SCHEMBL21826752 0.82 CA2 (0.50) CA1CA2CA4CA6CA12
SCHEMBL28930136 0.82 TRPV4 (0.44) GAAHSD11B1MMP2MMP9MMP8
SCHEMBL9379437 0.76 HSD11B1 (0.54) GAAHSD11B1MEN1KMT2AMMP2
SCHEMBL6680955 0.73 GAA (0.46) GAAHSD11B1MEN1KMT2AMMP2
SCHEMBL587387 0.73 MMP2 (0.44) GAAHSD11B1MEN1KMT2AMMP2
SCHEMBL1538924 0.73 GABRA1 (0.35) MEN1KMT2AHTR2CCA1CA2
SCHEMBL10887594 0.69 GAA (0.52) GAAMEN1KMT2AHTR6CA1
SCHEMBL4951439 0.69 MEN1 (0.32) MEN1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024139562-A1 PARTIALLY-DILUTED HIGH-CONCENTRATION ELECTROLYTE, PREPARATION METHOD THEREFOR, AND LITHIUM METAL BATTERY 北京恩力动力技术有限公司 2024-07-04 WO claimed
CN-115863762-A High-voltage lithium ion electrolyte and application thereof 赣州石磊新能源科技有限公司 2023-03-28 CN claimed
WO-2024139562-A1 PARTIALLY-DILUTED HIGH-CONCENTRATION ELECTROLYTE, PREPARATION METHOD THEREFOR, AND LITHIUM METAL BATTERY 北京恩力动力技术有限公司 2024-07-04 WO disclosed
US-20240166595-A1 PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS GENENTECH, INC. (US) 2024-05-23 US disclosed
EP-4347574-A1 PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS Genentech, Inc. (US) 2024-04-10 EP disclosed
CN-117379452-A Substituted nucleosides, nucleotides and analogues thereof 艾丽奥斯生物制药有限公司 2024-01-12 CN disclosed
CN-112174960-B Toll-like receptor modulating 4, 6-diamino-pyrido [3,2-D ] pyrimidine compounds 吉利德科学公司 2023-10-10 CN disclosed
CN-116364444-A High-temperature electrolyte for super capacitor 江苏国泰超威新材料有限公司 2023-06-30 CN disclosed
CN-115832422-A Gel polymer lithium ion electrolyte and battery containing same 赣州石磊新能源科技有限公司 2023-03-21 CN disclosed
CN-115820073-A Ultralong salt-fog-resistant water-based graphene modified epoxy primer heavy-duty anticorrosive paint and preparation method thereof 河北悠扬时代环保科技有限公司 2023-03-21 CN disclosed
WO-2022251567-A1 PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS GENENTECH, INC. (US) 2022-12-01 WO disclosed
CN-100335486-C Preparation method of [(phenyl sulfonyl) difluoro methyl] trimethyl silane SHANGHAI INST ORGANIC CHEM (CN) 2007-09-05 CN disclosed
WO-2005097739-A3 NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES UNIV SOUTHERN CALIFORNIA (US) 2006-05-18 WO disclosed
WO-2005097739-A2 NUCLEOPHILIC SUBSTITUTION REACTIONS OF DIFLUOROMETHYL PHENYL SULFONE WITH ALKYL HALIDES LEADING TO THE FACILE SYNTHESIS OF TERMINAL 1,1-DIFLUORO-1-ALKENES AND DIFLUOROMETHYLALKANES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-10-20 WO disclosed
EP-0672122-A1 OLIGONUCLEOTIDES WITH RNA CLEAVAGE ACTIVITY VPI HOLDINGS, LTD. (BM) 1995-09-20 EP disclosed
US-5442084-A Method of selective fluorination AIR PRODUCTS AND CHEMICALS, INC. (US) 1995-08-15 US disclosed
WO-1994013789-A2 OLIGONUCLEOTIDES WITH RNA CLEAVAGE ACTIVITY RIBONETICS GMBH (DE) 1994-06-23 WO disclosed
US-5175302-A Nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1992-12-29 US disclosed
US-4999429-A Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives ETHYL CORPORATION (US) 1991-03-12 US disclosed
US-4837327-A Process for nucleophilic fluoroalkylation of aldehydes ETHYL CORPORATION (US) 1989-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166595-A1 PROCESS FOR THE PREPARATION OF BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS CYP2C18, CYP2C19, CYP4X1 GAA 1606/4885HSD11B1 587/4885MEN1 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.