SCHEMBL7793393

SCHEMBL7793393

COc1ccc(C=NN=Cc2ccc(C)cc2F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 4/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NFE2L2 Q16236 6/20 0.47
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
AMY1A P0DUB6 1/20 0.46
ALDH1A1 P00352 1/20 0.44
CYP1A1 P04798 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP1B1 Q16678 2/20 0.44
CHRM5 P08912 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793389 1.00 RELA (0.50) RELANPC1RAB9ASMN1; SMN2NFE2L2
SCHEMBL7788710 0.91 AMY1A (0.52) RELANPC1RAB9ASMN1; SMN2NFE2L2
SCHEMBL7788708 0.91 AMY1A (0.52) RELANPC1RAB9ASMN1; SMN2NFE2L2
SCHEMBL7791874 0.89 AMY1A (0.56) RELANPC1NFE2L2GRIN2DGRIN3B
SCHEMBL7791870 0.89 AMY1A (0.56) RELANPC1NFE2L2GRIN2DGRIN3B
SCHEMBL7783562 0.87 NPC1 (0.63) NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D
SCHEMBL7783559 0.87 NPC1 (0.63) NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D
SCHEMBL7793109 0.84 NPC1 (0.43) NPC1RAB9ASMN1; SMN2NFE2L2GRIN2B
SCHEMBL7793110 0.84 NPC1 (0.43) NPC1RAB9ASMN1; SMN2NFE2L2GRIN2B
SCHEMBL7793229 0.84 NFE2L2 (0.56) NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed