Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803203 | 0.90 | POLB (0.51) | POLBCA2CA1CA5AMMP8 | |
| SCHEMBL7793406 | 0.86 | POLB (0.49) | POLBCA2CA1CA5ACA12 | |
| SCHEMBL7800969 | 0.85 | MMP2 (0.55) | POLBCA2CA1CA5ACA7 | |
| SCHEMBL7793435 | 0.77 | CA12 (0.52) | POLBCA2CA1CA5ACA7 | |
| SCHEMBL7798914 | 0.77 | POLB (0.48) | POLBCA2CA12CA9MMP1 | |
| SCHEMBL7793390 | 0.76 | KMT2A (0.57) | CA2CA12CA9KMT2A | |
| SCHEMBL7799262 | 0.75 | POLB (0.52) | POLBCA2CA12CA9MMP8 | |
| SCHEMBL7803207 | 0.74 | POLB (0.43) | POLBCA2CA1CA5AMMP8 | |
| SCHEMBL1329533 | 0.74 | SLC1A3 (0.56) | F10SLC1A3SLC1A2SLC1A1CA2 | |
| SCHEMBL13073722 | 0.72 | KMT2A (0.53) | POLBMMP2MMP9MMP8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143960-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | Roche Diagnostics GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027378-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |