Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799255 | 0.91 | L3MBTL1 (0.50) | KMT2ACTSLL3MBTL1RAB9ANPC1 | |
| SCHEMBL7798889 | 0.91 | NPC1 (0.64) | KMT2ACTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL7798884 | 0.88 | ALDH1A1 (0.58) | KMT2ACTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL7793435 | 0.85 | CA12 (0.52) | KMT2ACTSSCTSKALDH1A1HPGD | |
| SCHEMBL7799262 | 0.83 | POLB (0.52) | KMT2ACA12CA2CA9 | |
| SCHEMBL10073683 | 0.82 | CTSL (0.49) | KMT2ACTSLCTSSCTSKALDH1A1 | |
| SCHEMBL7798914 | 0.80 | POLB (0.48) | KMT2AALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL7793398 | 0.79 | L3MBTL1 (0.46) | KMT2ACTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL7793454 | 0.79 | MMP1 (0.64) | KMT2AALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL7793447 | 0.79 | MMP1 (0.64) | KMT2AALDH1A1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143960-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | Roche Diagnostics GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027378-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |