⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799067 | 0.84 | HCAR3 (0.33) | — | |
| SCHEMBL6985187 | 0.82 | PSMD14 (0.40) | — | |
| SCHEMBL6981930 | 0.82 | MAOB (0.43) | — | |
| SCHEMBL7802370 | 0.81 | ADORA2A (0.37) | — | |
| SCHEMBL7799351 | 0.79 | RAB9A (0.37) | — | |
| SCHEMBL7801071 | 0.73 | LRRK2 (0.33) | — | |
| SCHEMBL7799355 | 0.72 | HPGD (0.34) | — | |
| SCHEMBL8437417 | 0.69 | HCAR3 (0.33) | — | |
| SCHEMBL7799131 | 0.69 | PDK2 (0.36) | — | |
| SCHEMBL7801055 | 0.68 | HPGD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021860-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 1999-08-05 | — | — | WO | claimed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | disclosed |