Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707070 | 0.88 | PGR (0.57) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL6707066 | 0.88 | PGR (0.57) | PGRNR3C1TDP1LMNAPDE4D | |
| Potassium Ion SCHEMBL10883783 | 0.84 | PGR (0.70) | PGRNR3C1TDP1LMNAPDE4D | |
| Potassium Ion SCHEMBL10883779 | 0.84 | PGR (0.70) | PGRNR3C1TDP1LMNAPDE4D | |
| Potassium Ion SCHEMBL10945748 | 0.84 | PGR (0.70) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL7797159 | 0.83 | PGR (0.71) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL3737458 | 0.71 | CYP19A1 (0.44) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL10946077 | 0.71 | CYP19A1 (0.44) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL10886101 | 0.71 | CYP19A1 (0.44) | PGRNR3C1TDP1LMNAPDE4D | |
| SCHEMBL10886334 | 0.70 | PGR (0.69) | PGRNR3C1TDP1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863760-B1 | USE OF ANTIMINERALOCORTICOID COMPOUNDS AGAINST DRUG WITHDRAWAL SYNDROME | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |