Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793646 | 0.83 | NR5A1 (0.41) | RAB9ACNR2CNR1THRATHRB | |
| SCHEMBL5722804 | 0.82 | RAB9A (0.39) | RAB9ATHRATHRBS1PR3 | |
| SCHEMBL7920103 | 0.71 | RARB (0.46) | CNR2PLA2G4BFAAH | |
| SCHEMBL21431968 | 0.69 | KMT2A (0.45) | RAB9ACNR2CNR1KMT2ASMN1; SMN2 | |
| SCHEMBL8921620 | 0.68 | TP53 (0.61) | KMT2ASMN1; SMN2PLA2G4BESR1FAAH | |
| SCHEMBL7792455 | 0.67 | HTR1D (0.37) | RAB9ATHRATHRBS1PR3 | |
| SCHEMBL5722827 | 0.67 | HTR1D (0.33) | CNR2CNR1THRATHRB | |
| SCHEMBL15236082 | 0.66 | DGKA (0.46) | KMT2ASMN1; SMN2 | |
| SCHEMBL16307340 | 0.66 | NR5A1 (0.58) | RAB9AS1PR3PLA2G4B | |
| SCHEMBL10540387 | 0.65 | RARB (0.64) | KMT2ASMN1; SMN2PLA2G4BESR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946476-B1 | 5,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-21 | — | — | EP | disclosed |
| US-6159392-A | 5,7-difluoro-1,2,3,4-tetrahydronaphthalene derivatives and their use thereof in liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2000-12-12 | — | — | US | disclosed |