Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722708 | 0.92 | NR5A1 (0.41) | NR5A1RAB9AS1PR3HTR1DHTR1B | |
| SCHEMBL5722804 | 0.86 | RAB9A (0.39) | NR5A1RAB9AS1PR3HTR1DHTR1B | |
| SCHEMBL7796703 | 0.85 | SPHK1 (0.46) | LMNA | |
| SCHEMBL7793510 | 0.83 | RAB9A (0.40) | RAB9AS1PR3THRATHRBCNR2 | |
| SCHEMBL7935212 | 0.78 | NR5A1 (0.40) | NR5A1S1PR3THRATHRBLTA4H | |
| SCHEMBL8459322 | 0.78 | CRBN (0.47) | NR5A1S1PR3THRATHRBLMNA | |
| SCHEMBL5722827 | 0.76 | HTR1D (0.33) | NR5A1HTR1DHTR1BTHRATHRB | |
| SCHEMBL7796762 | 0.75 | TYR (0.37) | CNR2CNR1 | |
| SCHEMBL7793664 | 0.74 | CYP3A4 (0.42) | S1PR3LMNA | |
| SCHEMBL7792455 | 0.72 | HTR1D (0.37) | NR5A1RAB9AS1PR3HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946476-B1 | 5,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-21 | — | — | EP | disclosed |
| US-6159392-A | 5,7-difluoro-1,2,3,4-tetrahydronaphthalene derivatives and their use thereof in liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2000-12-12 | — | — | US | disclosed |