Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867070 | 0.82 | MAOB (0.51) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL7793594 | 0.81 | KMT2A (0.49) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6867371 | 0.80 | ALDH1A1 (0.56) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6869569 | 0.78 | MAOA (0.43) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6869570 | 0.77 | MAOA (0.43) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6869573 | 0.76 | KMT2A (0.45) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6867104 | 0.72 | MAOA (0.41) | MAOAMAOBKMT2AMEN1HSD17B10 | |
| SCHEMBL7794175 | 0.70 | GBA1 (0.42) | MAOAMAOBKMT2AHPGDALDH1A1 | |
| SCHEMBL6867776 | 0.70 | GBA1 (0.44) | MAOAMAOBKMT2AMEN1HPGD | |
| SCHEMBL6867087 | 0.69 | RAB9A (0.39) | MAOAMAOBKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |