Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784728 | 0.80 | NPC1 (0.49) | FDPSCA1CA12MAPTRAB9A | |
| SCHEMBL12890441 | 0.78 | KMT2A (0.52) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL7790447 | 0.76 | FDPS (0.69) | FDPSCA1MMP2CA12RAB9A | |
| SCHEMBL7697932 | 0.76 | MAPT (0.51) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL11016312 | 0.76 | MEN1 (0.63) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL16721275 | 0.75 | MAPT (0.50) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL16721273 | 0.75 | MAPT (0.50) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL31477687 | 0.75 | KMT2A (0.52) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL1669347 | 0.75 | KMT2A (0.52) | MAPTRAB9ANPC1PKMALDH1A1 | |
| SCHEMBL1669351 | 0.75 | KMT2A (0.52) | MAPTRAB9ANPC1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |