Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15163986 | 0.81 | FDPS (0.67) | FDPSCA12CA9CA1MMP2 | |
| SCHEMBL8167477 | 0.81 | FDPS (1.00) | FDPSCA12CA9CA1NPC1 | |
| SCHEMBL15163926 | 0.78 | FDPS (0.61) | FDPSCA12CA9CA2MMP2 | |
| SCHEMBL5155756 | 0.77 | FDPS (0.47) | FDPSNPC1RAB9ANR0B1 | |
| SCHEMBL7793597 | 0.76 | FDPS (0.60) | FDPSCA12CA1MMP2NPC1 | |
| SCHEMBL104084 | 0.74 | IDO1 (0.51) | FDPSMMP2NPC1RAB9ANR0B1 | |
| SCHEMBL7797073 | 0.74 | FDPS (0.61) | FDPSCA12CA9 | |
| SCHEMBL7790466 | 0.72 | PPIA (0.56) | FDPS | |
| SCHEMBL5156538 | 0.71 | FDPS (1.00) | FDPSCA12CA9NPC1RAB9A | |
| SCHEMBL7790669 | 0.71 | FDPS (0.54) | FDPSCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |