Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722700 | 0.93 | NR5A1 (0.40) | NR5A1CRBNLMNACNR2CNR1 | |
| SCHEMBL5722695 | 0.87 | CRBN (0.40) | NR5A1CRBNLMNACNR2CNR1 | |
| SCHEMBL7931886 | 0.86 | SPHK1 (0.40) | LMNATP53 | |
| SCHEMBL5722657 | 0.80 | CYP3A4 (0.32) | — | |
| SCHEMBL8459322 | 0.78 | CRBN (0.47) | NR5A1CRBNLMNAS1PR3TP53 | |
| SCHEMBL5722631 | 0.78 | CNR2 (0.34) | NR5A1CRBNCNR2CNR1 | |
| SCHEMBL7793646 | 0.78 | NR5A1 (0.41) | NR5A1CRBNLMNACNR2CNR1 | |
| SCHEMBL7932528 | 0.74 | CYP3A4 (0.34) | CNR2CNR1TP53TSHR | |
| SCHEMBL5722708 | 0.73 | NR5A1 (0.41) | NR5A1CRBNLMNACNR2CNR1 | |
| SCHEMBL7930592 | 0.73 | LTA4H (0.35) | NR5A1CRBNLMNACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944690-B1 | 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-28 | — | — | EP | disclosed |