Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7793780

C[n+]1c2ccccc2c(C(=O)Oc2c(Cl)cc(Cl)cc2Cl)c2ccccc21.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.35

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 8/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ACHE P22303 9/20 0.34
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL38661998 0.90 ACHE (0.36) KCNH2MAPTLMNAHTTNPSR1
Trifluoromethanesulfonic Acid SCHEMBL7048365 0.85 LMNA (0.33) MAPTLMNAHTTNPSR1
Trifluoromethanesulfonic Acid SCHEMBL38661855 0.85 KCNH2 (0.36) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7796557 0.85 CYP1A2 (0.35) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL38663634 0.83 TERT (0.35) KCNH2MAPTHTTACHE
Trifluoromethanesulfonic Acid SCHEMBL6587832 0.83 ACHE (0.35) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7796576 0.83 ACHE (0.38) KCNH2ACHEKMT2A
Trifluoromethanesulfonic Acid SCHEMBL38663630 0.83 ACHE (0.38) KCNH2ACHEKMT2A
Trifluoromethanesulfonic Acid SCHEMBL6256435 0.83 KCNH2 (0.39) KCNH2ACHEKMT2A
Trifluoromethanesulfonic Acid SCHEMBL5705540 0.82 MAPT (0.39) KCNH2MAPTNPSR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0750748-B1 NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2001-12-05 EP disclosed
US-5750698-A USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE LUMIGEN, INC. (US) 1998-05-12 US disclosed
US-5593845-A BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY LUMIGEN, INC. (US) 1997-01-14 US disclosed
WO-1995023971-A1 NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1995-09-08 WO disclosed