Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319548 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL5966245 | 0.83 | NR4A1 (0.52) | KDM4EALDH1A1HPGDTSHRMAPT | |
| SCHEMBL5746207 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL19856493 | 0.81 | EDNRA (0.32) | — | |
| SCHEMBL8314986 | 0.81 | MEN1 (0.45) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL8316081 | 0.81 | PLK1 (0.57) | KDM4EGAANSD2POLBBRD4 | |
| SCHEMBL8316214 | 0.81 | LMNA (0.44) | KDM4EALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL7119411 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL38573232 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL8315559 | 0.77 | TSHR (0.54) | KDM4EALDH1A1TSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697349-A | Nicotinamide mononucleotide derivatives for the treatment of bacterial infections | 努瓦米德股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |