Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249202 | 0.87 | ATM (0.47) | KDM4EALDH1A1GAAATMKMT2A | |
| SCHEMBL5966245 | 0.83 | NR4A1 (0.52) | KDM4EALDH1A1L3MBTL1HSD17B10MAPT | |
| SCHEMBL7793783 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL5748816 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAKMT2APARP1 | |
| SCHEMBL5748948 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1GAAKMT2APARP1 | |
| SCHEMBL8314986 | 0.77 | MEN1 (0.45) | KDM4EALDH1A1GAAKMT2AMAPT | |
| SCHEMBL8316081 | 0.77 | PLK1 (0.57) | KDM4EGAAL3MBTL1POLBNPC1 | |
| SCHEMBL8316214 | 0.77 | LMNA (0.44) | KDM4EALDH1A1ATMKMT2AHSD17B10 | |
| SCHEMBL6135290 | 0.77 | ATM (0.61) | KDM4EALDH1A1GAAATMKMT2A | |
| SCHEMBL19856493 | 0.74 | EDNRA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20020160413-A1 | COMBINATORIAL LIBRARIES | ROCHESTER, UNIVERSITY OF | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160413-A1 | COMBINATORIAL LIBRARIES | PICALM, ADGRE5, NGFR | KDM4E 4824/4885ALDH1A1 2441/4885GAA 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.