SCHEMBL19856493

SCHEMBL19856493

C=C(C)c1cccc2[c]cccc12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793783 0.81 KDM4E (0.42)
SCHEMBL30226722 0.77 EDNRA (0.42) EDNRA
SCHEMBL6903580 0.77 EDNRA (0.42) EDNRA
SCHEMBL5966245 0.76 NR4A1 (0.52)
SCHEMBL5746207 0.74 KDM4E (0.44)
SCHEMBL8316081 0.74 PLK1 (0.57)
SCHEMBL8316214 0.74 LMNA (0.44)
SCHEMBL8314986 0.74 MEN1 (0.45)
SCHEMBL12521035 0.72
SCHEMBL386156 0.71 CYP1A2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
CN-109154677-B Low viscosity agent for high refractive index polymerizable compound and polymerizable composition containing same 日产化学株式会社 2022-07-05 CN disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
CN-109071731-B Polymerizable composition containing reactive phenanthrene ring-containing silsesquioxane compound 日产化学株式会社 2021-08-13 CN disclosed
CN-109153691-B Polymerizable silane compound 日产化学株式会社 2021-07-09 CN disclosed
CN-109196008-B Reactive polysiloxane and polymerizable composition containing same 日产化学株式会社 2021-07-06 CN disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
US-10894800-B2 Polymerizable silane compound NISSAN CHEMICAL CORPORATION (JP) 2021-01-19 US disclosed
EP-3466956-B1 POLYMERIZABLE SILANE COMPOUND NISSAN CHEMICAL CORP (JP) 2020-12-09 EP disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
EP-3466994-A1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
EP-3466956-A1 POLYMERIZABLE SILANE COMPOUND Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
US-10253126-B2 Optical waveguide-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
EP-3444284-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING Nissan Chemical Corporation (JP) 2019-02-20 EP disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894800-B2 Polymerizable silane compound PCNA, ARL1, CCNE1 EDNRA 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.