SCHEMBL7793871

SCHEMBL7793871

COC(=O)c1c(Cl)nn(C)c1S(=O)(=O)NC(=O)Nc1cc(OC)cc(OC)n1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.40
CREBBP Q92793 1/20 0.40
GAA P10253 1/20 0.37
S1PR2 O95136 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
P2RY1 P47900 1/20 0.31
CDK1 P06493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9241921 0.92 FBP1 (0.40) FBP1CREBBPGAAS1PR2NPC1
SCHEMBL8703666 0.92 FBP1 (0.41) FBP1CREBBPGAAS1PR2ALDH1A1
SCHEMBL27258974 0.88 FBP1 (0.40) FBP1CREBBPGAAS1PR2L3MBTL1
SCHEMBL55094 0.85 GAA (0.52) GAAALDH1A1KDM4ETP53CDK1
SCHEMBL8358944 0.82 GAA (0.46) GAAALDH1A1SMN1; SMN2CDK1
Halosulfuron SCHEMBL22721319 0.82 GAA (0.48) GAAALDH1A1KDM4ETP53CDK1
SCHEMBL27313081 0.80 FBP1 (0.41) FBP1CREBBPGAAALDH1A1KDM4E
SCHEMBL27851615 0.78 FBP1 (0.34) FBP1CREBBPGAA
SCHEMBL5904842 0.78 RAB9A (0.46) FBP1CREBBPGAAALDH1A1KDM4E
SCHEMBL8358886 0.77 GAA (0.47) GAAALDH1A1KDM4ETP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010056040-A1 Controlling weeds; synergistic mixtures BAYER AKTIENGESELLSCHAFT KONZERNBEREICH RP PATENT UND LIZENZEN (DE) 2001-12-27 US disclosed
EP-0603240-B1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLUREAS MONSANTO CO (US) 1998-12-02 EP disclosed
US-5502025-A ANTIDOTES FOR HERBICIDES AND PLANT SAFTENING AGENTS MONSANTO COMPANY (US) 1996-03-26 US disclosed
CN-1061322-A The safe of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1992-05-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056040-A1 Controlling weeds; synergistic mixtures AS3MT, OSR1, MSRB3 FBP1 945/4885CREBBP 3694/4885GAA 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.