⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793941 | 0.86 | ALDH1A1 (0.37) | — | |
| SCHEMBL7759623 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL7795356 | 0.75 | — | — | |
| SCHEMBL7053117 | 0.75 | — | — | |
| SCHEMBL7053335 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL1289304 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL838347 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL3363301 | 0.72 | — | — | |
| SCHEMBL7761298 | 0.71 | — | — | |
| SCHEMBL10773422 | 0.71 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006118-B1 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | DOW CORNING ASIA LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6175031-B1 | PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE | DOW CORNING ASIA, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-6111126-A | Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond | DOW CORNING ASIA, LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-1006118-A2 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | Dow Corning Asia, Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |