SCHEMBL7053335

SCHEMBL7053335

CCO[Si](C)(Cl)OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793941 0.80 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL7056882 0.79 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL838934 0.76 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL839014 0.76 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL728864 0.76 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL3912974 0.74 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL3910859 0.74 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL28085493 0.74 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL467729 0.74
SCHEMBL502559 0.73 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed