Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789649 | 0.86 | CYP1A2 (0.39) | TSHRL3MBTL1ALDH1A1RNPEPKMT2A | |
| SCHEMBL7793701 | 0.86 | LMNA (0.44) | LMNAALDH1A1RNPEP | |
| SCHEMBL7794209 | 0.85 | HDAC3 (0.33) | RNPEPFOLH1 | |
| SCHEMBL7784218 | 0.83 | FOLH1 (0.42) | TSHRLMNAALDH1A1RNPEPKMT2A | |
| SCHEMBL7784245 | 0.81 | TSHR (0.39) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL29129028 | 0.81 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL15954875 | 0.81 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL7784226 | 0.78 | GSTK1 (0.44) | TSHRLMNAALDH1A1RNPEPKMT2A | |
| SCHEMBL8104827 | 0.78 | TSHR (0.48) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL7778506 | 0.76 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | claimed |
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |
| JP-2000001471-A | 6,8-DIMERCAPTO-OCTANOIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | GALDERMA RES & DEV SNC | 2000-01-07 | — | — | JP | disclosed |