SCHEMBL7794255

SCHEMBL7794255

Cc1cc(O)c(CCCCCC(=O)O)cc1O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F13A1 P00488 3/20 0.58
NPSR1 Q6W5P4 1/20 0.47
LTB4R Q15722 2/20 0.45
RXFP1 Q9HBX9 2/20 0.44
MAPT P10636 1/20 0.44
SCD O00767 1/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
PMP22 Q01453 1/20 0.41
FABP4 P15090 2/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 1/20 0.40
PRNP P04156 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3838212 0.93 NPSR1 (0.50) F13A1NPSR1TSHRFABP4POLB
SCHEMBL3833410 0.85 NPSR1 (0.64) NPSR1MAPTPOLBALDH1A1
SCHEMBL11315318 0.84 GPR84 (0.61) F13A1MAPTSCDTSHRFABP4
SCHEMBL11312068 0.84 GPR84 (0.61) F13A1MAPTSCDTSHRFABP4
SCHEMBL11322649 0.84 GPR84 (0.61) F13A1MAPTSCDTSHRFABP4
SCHEMBL11308530 0.84 GPR84 (0.61) F13A1MAPTSCDTSHRFABP4
SCHEMBL9158044 0.82 LMNA (0.45) NPSR1LMNATSHRFABP4POLB
SCHEMBL8092550 0.80 ALOX5 (0.58) MAPTTSHR
SCHEMBL9171102 0.80 ALOX5 (0.58) MAPTTSHR
SCHEMBL9792886 0.80 ALOX5 (0.58) MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526302-B1 Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica OREAL (FR) 1995-03-01 EP claimed
US-20010036446-A1 Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives L'OREAL (FR) 2001-11-01 US disclosed
US-5667792-A CARBOXY DERIVATIVES OF HYDROQUINONE AS BLEACHES FOR SKIN L'OREAL (FR) 1997-09-16 US disclosed
US-5637756-A TREATMENT OF SKIN DISORDERS, BLEACHING OF PIGMENTED SPOTS, COSMETICS L'OREAL (FR) 1997-06-10 US disclosed
US-5587173-A Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action L'OREAL (FR) 1996-12-24 US disclosed
US-5585105-A Utilization of derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action L'OREAL (FR) 1996-12-17 US disclosed
US-5449518-A Bleaching, decoloring skin L'OREAL (FR) 1995-09-12 US disclosed