Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 4/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794271 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TDP1SMN1; SMN2GJB2PTAFR | |
| SCHEMBL5008878 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2GJB2PTAFR | |
| SCHEMBL10765035 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2GJB2PTAFR | |
| SCHEMBL5008877 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2GJB2PTAFR | |
| SCHEMBL3979922 | 0.88 | ALDH1A1 (0.40) | ALDH1A1TDP1SMN1; SMN2GJB2PTAFR | |
| SCHEMBL12000846 | 0.86 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2GJB2PPP5C | |
| SCHEMBL14580119 | 0.86 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2GJB2PPP5C | |
| SCHEMBL17867772 | 0.81 | GJB2 (0.42) | ALDH1A1TDP1SMN1; SMN2GJB2GBA1 | |
| SCHEMBL17867773 | 0.81 | GJB2 (0.42) | ALDH1A1TDP1SMN1; SMN2GJB2GBA1 | |
| SCHEMBL14038310 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1TDP1SMN1; SMN2GJB2PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777674-B1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | BAYER AG (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0777674-A1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | CHIRON CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5597909-A | Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use | CHIRON CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| US-5594117-A | Polynucleotide reagents containing modified deoxyribose moieties and associated methods of synthesis and use | CHIRON CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996006104-A1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | CHIRON CORPORATION (US) | 1996-02-29 | — | — | WO | disclosed |