Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.51 |
| ▸ | DRD5 | P21918 | 3/20 | 0.51 |
| ▸ | HRH2 | P25021 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL9600777 | 0.96 | KMT2A (0.54) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9602476 | 0.91 | DRD3 (0.51) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| SCHEMBL7767918 | 0.89 | LMNA (0.53) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9602731 | 0.88 | MEN1 (0.52) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7796036 | 0.88 | LMNA (0.52) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7920769 | 0.88 | LMNA (0.52) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| SCHEMBL7773850 | 0.87 | MAPT (0.67) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| SCHEMBL7794410 | 0.87 | LMNA (0.52) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL9601471 | 0.86 | SIGMAR1 (0.48) | DRD3DRD2SIGMAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL7794406 | 0.86 | LMNA (0.51) | DRD3DRD2SIGMAR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673368-B1 | NOVEL NICOTINIC ACID ESTERS | BIOVITRUM AB (SE) | 2001-11-28 | — | — | EP | claimed |
| EP-0673368-B1 | NOVEL NICOTINIC ACID ESTERS | BIOVITRUM AB (SE) | 2001-11-28 | — | — | EP | disclosed |